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The amount of data on the use of metoprolol in pregnant women is limited.
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Not all possible drug interactions are listed here.
While once daily dosing is effective and can maintain a reduction in blood pressure throughout the day, lower doses especially mg may not maintain a full effect at the end of the hour period, and larger or more frequent daily doses may be required.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Also, if you suddenly stop taking metoprolol for high blood pressure, chest pain, or after a heart attack, you raise your risk of heart attack.
The geriatric population may show slightly higher plasma concentrations of metoprolol as a combined result of a decreased metabolism of the drug in elderly population and a decreased hepatic blood flow.
Metoprolol Succinate ER reviews.
Metoprolol tartrate and metoprolol succinate can both treat high blood pressure and angina.
They may decrease blood pressure too much when combined with metoprolol.
Drug Status Rx.
Metoprolol Tartrate.
Because these reports are from a population of uncertain size and are subject to confounding factors, it is not possible to reliably estimate their frequency.
Always check that your prescription is correct.
Metoprolol Succinate ER.
Significant beta-blocking effect as measured by reduction of exercise heart rate occurs within one hour after oral administration, and its duration is dose related.
Greater care is required with use in those with liver problems or asthma.
Common side effects include trouble sleeping, feeling tired , feeling faint , and abdominal discomfort.
Metoprolol Succinate ER is a beta-blocker that affects the heart and circulation blood flow through arteries and veins.
Beta-blockers may mask tachycardia occurring with hypoglycemia, but other manifestations such as dizziness and sweating may not be significantly affected.
Warning Oral route Tablet, Extended Release Exacerbations of angina pectoris and, in some cases, myocardial infarction have occurred after abrupt cessation of therapy with certain beta-blocking agents.
Late Treatment Start patients with contraindications to treatment during the early phase of suspected or definite myocardial infarction, patients who appear not to tolerate the full early treatment, and patients in whom the physician wishes to delay therapy for any other reason on metoprolol tartrate tablets, mg twice daily, as soon as their clinical condition allows.
This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
See also: Metoprolol drug interactions in more detail.
Metoprolol injection is used during the early phase of a heart attack to lower the risk of death.
Digitalis Glycosides and Beta-Blockers Both digitalis glycosides and beta-blockers slow atrioventricular conduction and decrease heart rate.
This list is not complete and many other drugs may affect Metoprolol Succinate ER.
Along with its needed effects, metoprolol the active ingredient contained in Metoprolol Succinate ER may cause some unwanted effects.
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Pediatric Use Safety and effectiveness in pediatric patients have not been established.
Hypersensitivity to metoprolol and related derivatives, or to any of the excipients; hypersensitivity to other beta-blockers cross-sensitivity between beta-blockers can occur.
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Metoprolol is used for a number of conditions, including hypertension , angina , acute myocardial infarction , supraventricular tachycardia , ventricular tachycardia , congestive heart failure , and prevention of migraine headaches.
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Serious side effects and their symptoms can include the following:.
Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

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Many people have it for years without knowing it.
Both medications belong to a class of drugs called beta-blockers , which work by relaxing your blood vessels and slowing down your heart rate.
Follow all directions on your prescription label and read all medication guides or instruction sheets.
In some cases, they may not be available in all strengths or forms as the brand-name drugs.
Metoprolol has no intrinsic sympathomimetic activity, and membrane-stabilizing activity is detectable only at doses much greater than required for beta-blockade.
In several studies of patients with acute myocardial infarction, intravenous followed by oral administration of metoprolol caused a reduction in heart rate, systolic blood pressure and cardiac output.
Examples of MAOIs include:.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Other clinical manifestations of overdose should be managed symptomatically based on modern methods of intensive care.
In controlled clinical studies, metoprolol has been shown to be an effective antihypertensive agent when used alone or as concomitant therapy with thiazide-type diuretics, at dosages of mg to mg daily.
Chronically administered beta-blocking therapy should not be routinely withdrawn prior to major surgery; however, the impaired ability of the heart to respond to reflex adrenergic stimuli may augment the risks of general anesthesia and surgical procedures.
Use the medicine exactly as directed.
For seniors: Seniors may need a smaller dosage of metoprolol at first.
There are no adequate and well controlled studies in pregnant women.
Use During Major Surgery Chronically administered beta-blocking therapy should not be routinely withdrawn prior to major surgery; however, the impaired ability of the heart to respond to reflex adrenergic stimuli may augment the risks of general anesthesia and surgical procedures.
Journal of Medical Toxicology.
Drugs used to treat depression and other mood disturbances are processed in your body by the same systems as metoprolol.
Ergot alkaloids, such as dihydroergotamine, narrow blood vessels to treat headaches.
Tell your doctor if you are pregnant or plan to become pregnant.
Angina is a condition marked by a crushing chest pain.
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Hematologic Agranulocytosis, nonthrombocytopenic purpura and thrombocytopenic purpura.
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May precipitate a thyroid storm if abruptly stopped.
Hypersensitive Reactions Fever combined with aching and sore throat, laryngospasm and respiratory distress.
Vomiting was a common occurrence.
Speak to your doctor about how drug interactions should be managed.
Do not substitute metoprolol succinate with metoprolol tartrate.
Pruritus or rash have occurred in about 5 of patients.
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Metoprolol is also used to lower your risk of death or needing to be hospitalized for heart failure.
Metoprolol was first discovered in by Bengt Ablad and Enar Carlsson.
Metoprolol Tartrate side effects in more detail.
Biomedical Chromatography.
Skip the missed dose and use your next dose at the regular time.
It is also used to lower your risk of death or needing to be hospitalized for heart failure.
To detect if beta blockers have been used trace analysis of human urine is analyzed.
Calcium Channel Blockers Concomitant administration of a beta-adrenergic antagonist with a calcium channel blocker may produce an additive reduction in myocardial contractility because of negative chronotropic and inotropic effects.

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This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Warn patients not to interrupt or discontinue therapy without physician advice.
You should not use this medicine if you are allergic to Metoprolol Tartrate, or other beta-blockers atenolol , carvedilol , labetalol , nadolol , nebivolol , propranolol , sotalol , and others , or if you have:.
These drugs are often used to treat similar conditions.
Interactions Medicines that interact with metoprolol may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with metoprolol.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Metoprolol Succinate ER drug interactions in more detail.
Learn more about the similarities and differences between these two drugs.
One drug cannot be substituted for the other.
Drug manufacturers, however, are unable to advertise beta blockers for other purposes that have not been approved by the FDA.